Our Process

Our cutting edge production of a functional heart through tissue engineering involves several intricate steps. Initially, the process starts by isolating skin cells from the patient, typically through a small biopsy. These cells are then reprogrammed into induced pluripotent stem cells (iPSCs), which possess the ability to differentiate into various cell types. The next step involves guiding the differentiation of iPSCs into cardiac and endothelial cells using specialized growth factors and culture conditions. Once a sufficient number of cells are generated, the cardiac, endothelial, and support cells are combined and organized into a three-dimensional structure using advanced bioprinting techniques. This bioink, composed of the patient's own cells, forms the basis of the printed heart. Subsequently, the bioprinted heart is trained in a bioreactor system to mimic the natural environment and promote tissue maturation. This training process is crucial for optimizing the functionality and durability of the printed heart. Finally, when the engineered heart reaches a suitable level of maturity, it can be transplanted back into the patient. This groundbreaking and personalized procedure eliminates the risk of rejection since the transplanted heart is composed of the patient's own cells, offering a potentially life-saving solution.